Category Archive : Medical Knowledge

Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

It’s a type of Blood Cancer that starts in the bone marrow the soft inner parts of the bone. Though it can happen in other blood-forming cells as well it primarily happens in blood cells that may turn into white cells. Acute Myeloid Leukemia bone marrow cells don’t grow the desired way but it starts generating immature cells that are called blasts.

If proper treatment not given Acute Myeloid Leukemia can spread to blood and other parts of your body, such as your:

  • Lymph Nodes
  • Liver
  • Spleen
  • Brain and Spinal cord
  • Testicles

Your recovery can be better in case of following conditions-

  • Your age is less than 60.
  • At the time of diagnosis, your white blood cell count is lower.
  • You have not had past history of blood disorder or Cancer.
  • You don’t have a certain gene or chromosome changes.

There is no clear reason why AML happens to a person.There are some risk factors that may lead a person to this disease like-

  • Smoking
  • Exposure to certain chemicals such as benzene which is used in oil refineries, ionizing radiation, pesticides, and detergents.
  • Some blood condition such as Myeloproliferative disorder
  • Some Chemotherapy drugs used to treat cancer such as melphalan, mitoxantrone, and doxorubicin.
  • Exposure to high degree of radiation

As there is no clear reason its prevention is difficult but smoking and exposure to chemicals explained above can be avoided to lower risk.

Symptoms

  • Fever
  • Fatigue
  • Loss of Appetite
  • Headache
  • Usual bleeding
  • Swollen lever or spleen
  • Swollen gums

Acute Myeloid Leukemia Treatment

Since AML spreads faster, it’s important to begin treatment as early as possible. It depends on several things like how much it has spread and your overall health. Treatment can be in two phases- Remission induction therapy-This involves the killing of leukemic cells in your blood and bone marrow so you go into remission with no sign of diseased cells. Further in post-remission therapy remaining infected cells killed if there is any to avoid chances of disease coming back. The main treatment methods are like Chemotherapy, Radiation, and Stem cell transplant. For more related topic click on it Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

It’s a type of cancer of blood and Bone marrow which affects white blood cells, it occurs when bone marrow develops error in its DNA.The word acute in the name of this disease occurs from the fact that it grows rapidly and creates immature blood cells rather that mature ones.The word lymphoblastic refers to white blood cells called lymphocytes. This disease is also known at Acute Lymhoblastic Leukemia.

This disease is the most common type of cancer which happens in children and after treatment, there is a high chance of recovery but in adults chances of getting cured are relatively weak.

Symptoms:

  • Bleeding from the gums
  • Bone pain
  • Fever
  • Pale skin
  • Shortness of breath
  • Fatigue of general decrease in Energy

Many signs of symptoms mentioned above are of flu but if symptoms doesn’s improve then one should decide about doctor consultation.

Causes: It Occurs when bone marrow cells develop error in its DNA, as a result of which cells continue growing and dividing. While a normal cell would stop dividing and ultimately die, the disease cell will lead to the abnormal production of immature cells that would not function properly and crowd out healthy cells. These immature cells that develop in the leukemic white cells are called lymphoblasts. This is not clear how faulty DNA mutations happen but doctors have found that most cases of Acute Lymphoblastic Leukemia are not inherited.

Risk Factors: Factors that may increase risk of this disease may include:

Previous cancer treatment:if there have been Chemotherapy or radiation therapy for other types of cancer then there is high risk of developing this disease.

Exposure to Radiation: People who are exposed to high degree radiation such as survivors of nuclear accidents may have a high risk of developing Acute Lymphoblastic Leukemia.

Genetic Disorder: Certain genetic disorders such as down syndrome is associated with an increased risk of this disease.